The star has donated the entirety of his £25k award prize money to the trust for venues, which works to preserve the Britain's independent live music spots.
Fender was given the award on October 16 as his new release People Watching was declared the best record of the last 12 months.
He has decided to donate the funds to the MVT, in appreciation of the vital role grassroots venues had in his early career.
"I personally wouldn't be doing my current career if it hadn't been for all the performances I performed around the area, and further afield, when I was just getting going," remarked the artist. "These locations are renowned, but they are struggling."
From early 2023 onward, at least 150 of these spaces have ceased operations – about 16% of the total UK scene.
Recently, top acts such as Pulp, the group Coldplay, Katy Perry and Ed Sheeran have all supported the MVT in its initiatives to help venues survive, by applying a small levy to their ticket costs, which supports local stages.
Sam Fender also took part, raising in excess of £100,000 on his 2024 arena tour to support 38 small stages across Britain.
The donation assisted venues that were facing imminent closure due to issues stemming from water damage, fires and family tragedies, as well as permit problems, conflicts and noise complaints.
Some locations were granted financial assistance in improving facilities and sound and lighting systems that positively impacted artists and audiences.
"The notion that funds from performances in big venues helps the independent spots, where it all starts for artists like me, is just common sense," Sam Fender has said.
He is not the first artist to give his honor prize money to charitable organizations.
Back when they won the trophy in the year 1996 for their release Different Class, frontman Cocker declared that the act would donate their winnings to the organization War Child.
During 2002, rapper and singer she divided her award between a few good causes, including the NSPCC and a charity for Sickle Cell.
"And I donated a grand to my local community centre, to their gymnastics class, because I practiced gymnastics when I was younger and they required new equipment," she explained to a publication.
Two years ago, the band contributed their funds to the community center that nurtured their act, in addition to other local music groups.
Also winners that year the group donated their award to a MS organization after a close contact was diagnosed the condition.
"Receiving the award was quite enough," remarked artist Heather Small. "The money was the cherry on top but we could do without the extra, because we had the main prize. So our success affected somebody else's life."
In the past week, the Music Venues Trust shared it had saved two small stages in that region, by bringing them into community ownership.
One venue in the city and the second in the city were acquired under the public acquisition initiative, which is funded by Arts Council England and enthusiasts who acquire "stakes" in the properties.